@Srgio727 @TheCensoredRock @Magnor1108 But asymptomatic also means fewer viruses, & less viral opportunity to escape the body, since targeted response is a more efficient way to stop infection. Gotta realize, unvax response is just inflammation IF re
@1goodtern In October 2022, Krogan Lab discussed innate immune evasion as the second-strongest selective pressure on SARS-CoV-2. Other papers such as Thorne et al https://t.co/iV8KUPEhKK, Lin and Gack https://t.co/Ya4Hrv64XW, and Guo et al https://t.co/UFt
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
@thuisblijvend @mkeulemans Ik heb nog aanvullingen t.a.v. de onmogelijkheid van immuniteit voor SARS/COVID: (1): SARS evolueert om het immuunsysteem beter te omzeilen: https://t.co/IkWooekCMB
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
RT @LongDesertTrain: This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perh…
This has been noted by the masterful @KroganLab. Alpha had the highest ORF9b sgRNA expression of any variant and, perhaps not coincidentally, remains the "the best overall innate immune suppressor" of any variant. https://t.co/m44356GZha 44/ https://t.co
RT @T_Brautigan: https://t.co/iovMYLfnKV @GuptaR_lab look at the shallower gradient if the bf.5 wave in Japan
https://t.co/iovMYLfnKV @GuptaR_lab look at the shallower gradient if the bf.5 wave in Japan
@JPWeiland @chrischirp Innate immune evasion is likely being selected for. https://t.co/sq2ISuAWCp
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/AmqSiSTVs1 #covid19
RT @_ppmv: "SARS-CoV-2 does appear to be more proficient at inhibiting natural immunity than other potentially lethal respiratory viruses,…
Shame we've been treating it like the flu, then
RT @_ppmv: "SARS-CoV-2 does appear to be more proficient at inhibiting natural immunity than other potentially lethal respiratory viruses,…
RT @_ppmv: "SARS-CoV-2 does appear to be more proficient at inhibiting natural immunity than other potentially lethal respiratory viruses,…
RT @T_Brautigan: Phosphorylation is fun for anyone who wants to dive deep into mutations imho @EricTopol https://t.co/iovMYLfnKV
Phosphorylation is fun for anyone who wants to dive deep into mutations imho @EricTopol https://t.co/iovMYLfnKV
RT @_ppmv: @annette_bulut Nicht nur das, SARS-COV-2 dysreguliert das Komplementsystem ähnlich wie Krebs selbst. Einer von vielen vermuteten…
@annette_bulut Nicht nur das, SARS-COV-2 dysreguliert das Komplementsystem ähnlich wie Krebs selbst. Einer von vielen vermuteten Mechanismen: https://t.co/FEVQJwQfbm
RT @_ppmv: @GovernmentTrav1 @NoyesJHumphrey @Welnesschick @fitterhappierAJ Two references, if useful. https://t.co/aooaxDZNn6 https://t.co…
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/3QAtxGDMSe
@keisuke4713 ➡️Omicron系統が自然免疫に適応続ける事に一致 コロナ症例と入院⬆️⬆️寄与? OmicronのOrf6・N発現⬆️ AlphaのOrf6、Orf9b、N発現⬆️連想、自然免疫と戦う共通適応か コロナ:強化した自然免疫回避の進化 https://t.co/TVDXxjyWsN antagonist蛋白発現⬆️➡️より効果的自然免疫⬇️ 感染成功⬆️複製と感染期間⬆️
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/2jeQhk2oMQ #covid19
@GermanCucumber1 @DrPatSoonShiong This is not for me to say, a question to researchers and clinicians. I’m not sure whether a consistent image has formed yet in the scientific community, it is contentious and complex so far. People like @fitterhappierAJ @W
Open Access UCL Research: Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/OtP2tOQXfi
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/MRvlps901g #covid19
@KazBowen ある変異ウイルスの他に対する優位性を何が決定するかを一概に言うことは難しいですが、構成タンパク質以外による免疫逃避はアルファ(B.1.1.7)にもあります。 https://t.co/5YcI4DeRGS
RT @KashPrime: @EvaMariaAnna Another important issue is immune evasion by SARS2, well documented by multiple studies. The vaccine does not…
RT @KashPrime: @EvaMariaAnna Another important issue is immune evasion by SARS2, well documented by multiple studies. The vaccine does not…
@EvaMariaAnna Another important issue is immune evasion by SARS2, well documented by multiple studies. The vaccine does not contain any of the sequences or proteins that contribute to disabling your immune responses: https://t.co/cqCW2NdHyu
@GovernmentTrav1 @NoyesJHumphrey @Welnesschick @fitterhappierAJ Two references, if useful. https://t.co/aooaxDZNn6 https://t.co/FEVQJwQfbm
"SARS-CoV-2 does appear to be more proficient at inhibiting natural immunity than other potentially lethal respiratory viruses, like influenza." It "targets the function of key MHC class I transcriptional regulators" like cancer. https://t.co/znUu4atUgP
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/14EKrkisTf #covid19
RT @raouljdegroot: SARS CoV2 evolutie wordt niet alleen gedreven door adaptieve (antilichamen tegen spike, CTLs) maar ook aangeboren immun…
RT @raouljdegroot: SARS CoV2 evolutie wordt niet alleen gedreven door adaptieve (antilichamen tegen spike, CTLs) maar ook aangeboren immun…
RT @raouljdegroot: SARS CoV2 evolutie wordt niet alleen gedreven door adaptieve (antilichamen tegen spike, CTLs) maar ook aangeboren immun…
SARS CoV2 evolutie wordt niet alleen gedreven door adaptieve (antilichamen tegen spike, CTLs) maar ook aangeboren immuniteit. Onze intracellulaire verdedigingsmechanismen selecteren op varianten die zich daar weer onderuit wurmen. https://t.co/6pogMvzZB
@sassybibrarian @michaelmina_lab You would have to see original tweet. The bridge is our T cells which normally are stable and help us But Covid can hurt the bridge/immune system pretty freq’ I vaccinate to keep antibodies circulating and wear hifi masks.
@DFla56 @lab5023 @eneldiluvio @alexmeshkin If he (a T cell immunologist Johns Hopkins)& many scientists are wrong, at worst, we wear unnecessary masks. If you’re wrong, there will be a lot more death, disability & suffering. They are projecting a
@CStokhof @JACS1924 @fitterhappierAJ Someone was nice to collect some information. It needs to be said that there are lots of scientists calling these theory wrong. So it is not that they are all on the same page here. I think it needs more time to be s
RT @abledoc: The ORF9b mutations demonstrated in this study using Alpha Variant are shared with Delta & Omicron. ORF9b interferes Tom70-MA…
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/vDAUTmGyfH #covid19
RT @KroganLab: Here is a link to our paper out today in @Nature https://t.co/KuSrpU5Aqz
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/mO9cEPZus1 #covid19
@DonaldVinh @Vadeboncoeur_Al @clicjf @jeanbarbeau2 @VeilletteAndre Exemple de mutations qui module la réponse Interferon selon les variants: https://t.co/6JBJhEeYmk
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/l20lLsY4pT #covid19
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/lR1NLBCab6 #covid19
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/owiroHYXeA #covid19
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/QBqPkMnHdc #covid19
2/5 Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/w2VuHwY3kN SARS-CoV-2->Orf9b->inhibits TOM70->inhibits MAVS-> suppresses innate immune response->augments SARS-COV-2 infection @LaskerFDN @RiceLaboratory @KroganLab,
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/P7CjDmtlYg #covid19
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/2bnpiJSSMP #covid19
Dominant Alpha variant evolved to evade our innate immune system https://t.co/cZGGqyryjB https://t.co/omkmSq3LkA https://t.co/1tXZcJmcDo
RT @manuelacasasoli: Two interesting articles to deeply understand the molecular #evolution and #adaptation of SARS-CoV-2 to humans. Mutati…
RT @manuelacasasoli: Two interesting articles to deeply understand the molecular #evolution and #adaptation of SARS-CoV-2 to humans. Mutati…
RT @manuelacasasoli: Two interesting articles to deeply understand the molecular #evolution and #adaptation of SARS-CoV-2 to humans. Mutati…
Two interesting articles to deeply understand the molecular #evolution and #adaptation of SARS-CoV-2 to humans. Mutations in the spike protein and outside enabled the virus to evade the body’s immune defenses. #Science #Omicron ⏯️https://t.co/RzCvGsikAa ⏯
RT @NatureKorea: SARS-CoV-2에 의한 강화된 선천성 면역 회피의 진화 하이라이트 | 네이처 2022년2월17일호 https://t.co/ughtcKXS1p
SARS-CoV-2에 의한 강화된 선천성 면역 회피의 진화 하이라이트 | 네이처 2022년2월17일호 https://t.co/ughtcKXS1p
Evolution of enhanced innate immune evasion by SARS-CoV-2 | Nature https://t.co/Z7zXcXpdaw
"The importance of mutations outside Spike in adaptation of SARS-CoV-2 to humans is underscored by the observation that similar mutations exist in the Delta and Omicron N/Orf9b regulatory regions." #OmicronVariant #COVID19 https://t.co/Ra8FVyYeNW
@threadreaderapp unroll please
RT @KroganLab: How do SARS-CoV-2 variants evolve to become more transmissible? One contributor, which we report today in @Nature, is increa…
RT @KroganLab: How do SARS-CoV-2 variants evolve to become more transmissible? One contributor, which we report today in @Nature, is increa…
RT @ykmohanta: #INPST
RT @ykmohanta: #INPST
RT @ykmohanta: #INPST
RT @ykmohanta: #INPST
RT @KroganLab: How do SARS-CoV-2 variants evolve to become more transmissible? One contributor, which we report today in @Nature, is increa…
RT @RTurniansky: @AlQasemJamal @fitterhappierAJ I have sources for literally all of these claims: https://t.co/cDvKP8Pt8W https://t.co/eH…
@AlQasemJamal @fitterhappierAJ I have sources for literally all of these claims: https://t.co/cDvKP8Pt8W https://t.co/eHYOE6rL7G https://t.co/jlZxeGDDt2 https://t.co/0mvS4a5v6k https://t.co/FKS6NSDEi3 https://t.co/k0KT1jASVa
Evolution of enhanced innate immune evasion by SARS-CoV-2 https://t.co/uLARQeZl80 #science #genomics
RT @UCSF_RDO: Evolution of enhanced innate immune evasion by SARS-CoV-2: mutations outside Spike are important to adaptation of SARS-CoV-2…